For the cell biologist, identifying changes in gene expression using DNA microarrays is just the start of a long journey from tissue to cell. We discuss how chip users can first filter noise ...

BOSTON--Gene expression microarrays have made a profound impact on biomedical research. The current expectation is that this technology will extend its current role as an experimental tool for basic ...

One bottleneck in next-generation sequencing is genomic sample selection. As research groups tackle the problem, companies are seizing a market opportunity. Ken Garber reports. The transformative ...

Reading the fluorescent signals on microarrays that give a glimpse into cellular gene expression is typically the job of laser scanners. This technology works well, but lasers can be very cumbersome ...

The enormous potential of miRNAs is driving new technologies for research, diagnostic, and therapeutic applications. miRNAs, a class of small noncoding RNAs of 19–30 nucleotides in length, regulate ...

Nature uses a common framework when building organisms as different as yeast, worms, fruit flies, mice, and humans. This makes it possible for scientists to learn about how our own genes work by ...

When it comes to enzymes, protein abundance does not necessarily translate into protein activity: Post-translational modifications such as phosphorylation can dramatically alter enzyme function.

Genomatix Software GmbH today announced that it has achieved GeneChip-compatible TM status for several products with the Affymetrix Inc. (Nasdaq: AFFX) GeneChip® microarray platform and that it has ...

Intense Dose-Dense Sequential Chemotherapy With Epirubicin, Paclitaxel, and Cyclophosphamide Compared With Conventionally Scheduled Chemotherapy in High-Risk Primary Breast Cancer: Mature Results of ...